RT Book, Section A1 Birlea, Stanca A. A1 Spritz, Richard A. A1 Norris, David A. A2 Goldsmith, Lowell A. A2 Katz, Stephen I. A2 Gilchrest, Barbara A. A2 Paller, Amy S. A2 Leffell, David J. A2 Wolff, Klaus SR Print(0) ID 56043354 T1 Chapter 74. Vitiligo T2 Fitzpatrick's Dermatology in General Medicine, 8e YR 2012 FD 2012 PB The McGraw-Hill Companies PP New York, NY SN 978-0-07-166904-7 LK accessmedicine.mhmedical.com/content.aspx?aid=56043354 RD 2024/04/20 AB |PrintVitiligo at a GlanceThe most frequent depigmenting disorder, affecting 0.3%–0.5% of the population worldwideAn acquired disease involving multiple genes and nongenetic environmental factorsCharacterized by progressive autoimmune-mediated destruction of epidermal melanocytesTypical presentation: patches of white skin and hairCause of physiological and social stigma among affected individualsIncreased risk for other autoimmune diseases, unpredictable evolution and unsatisfactory therapeutic outcomes