RT Book, Section
A1 Leiferman, Kristin M.
A1 Peters, Margot S.
A2 Goldsmith, Lowell A.
A2 Katz, Stephen I.
A2 Gilchrest, Barbara A.
A2 Paller, Amy S.
A2 Leffell, David J.
A2 Wolff, Klaus
SR Print(0)
ID 56031694
T1 Chapter 36. Eosinophils in Cutaneous Diseases
T2 Fitzpatrick's Dermatology in General Medicine, 8e
YR 2012
FD 2012
PB The McGraw-Hill Companies
PP New York, NY
SN 978-0-07-166904-7
LK accessmedicine.mhmedical.com/content.aspx?aid=56031694
RD 2024/04/24
AB |PrintEosinophils  in  Cutaneous  Diseases  at  a  GlanceEosinophils  may  be  seen  in  skin  biopsy  specimens  from  a  broad  range  of  cutaneous  diseases  but  are  not  pathognomonic  for  any  dermatosis.Eosinophils  are  an  important  component  of  the  characteristic  histologic  pattern  in  a  limited  number  of  diseases,  including  the  following:  Angiolymphoid  hyperplasia  with  eosinophiliaEosinophilic,  polymorphic,  and  pruritic  eruption  associated  with  radiotherapyEosinophilic  pustular  folliculitisErythema  toxicum  neonatorumEosinophilic  ulcer  of  the  oral  mucosaEosinophilic  vasculitisGranuloma  facialeHypereosinophilic  syndromesIncontinentia  pigmentiKimura  diseasePachydermatous  eosinophilic  dermatitisWells  syndrome  (eosinophilic  cellulitis)Clinical  reaction  patterns  with  eosinophil  involvement  include  diseases  in  which  eosinophils  probably  play  a  pathogenic  role  and  are  a  component  of  the  histological  pattern,  but  are  not  essential  for  diagnosis.Evidence  for  involvement  of  eosinophils  in  cutaneous  diseases  is  provided  by  observation  of  intact  eosinophils  in  lesional  tissue  sections  and/or  by  immunostains  for  their  toxic  granule  proteins,  which  are  deposited  in  tissues.