RT Book, Section
A1 Gladman, Dafna D.
A1 Chandran, Vinod
A2 Goldsmith, Lowell A.
A2 Katz, Stephen I.
A2 Gilchrest, Barbara A.
A2 Paller, Amy S.
A2 Leffell, David J.
A2 Wolff, Klaus
SR Print(0)
ID 56026285
T1 Chapter 19. Psoriatic Arthritis
T2 Fitzpatrick's Dermatology in General Medicine, 8e
YR 2012
FD 2012
PB The McGraw-Hill Companies
PP New York, NY
SN 978-0-07-166904-7
LK accessmedicine.mhmedical.com/content.aspx?aid=56026285
RD 2024/04/23
AB |PrintPsoriatic  Arthritis  at  a  GlancePsoriatic  arthritis  (PsA)  is  an  inflammatory  arthritis  associated  with  psoriasis  and  seronegative  for  rheumatoid  factor.Genetic  and  environmental  factors  underlie  susceptibility  to  PsA  and  immune-mediated  inflammation  leads  to  inflammation  in  musculoskeletal  structures.Clinical  features  of  PsA  include  peripheral  and  axial  arthritis,  enthesitis,  dactylitis,  and  tenosynovitis.Extra-articular  involvement  in  addition  to  skin  and  nail  involvement  may  include  conjunctivitis,  uveitis,  and  inflammatory  bowel  disease.Investigations  may  reveal  elevated  acute  phase  reactants,  although  conventional  tests  such  as  erythrocyte  sedimentation  rate  and  C-reactive  protein  are  normal  in  up  to  50%  of  patients.Radiographs  may  reveal  soft-tissue  swelling,  periostitis,  erosions,  pencil-in-cup  change,  ankylosis,  sacroiliitis,  or  syndesmophytes.Pharmacotherapy  is  the  mainstay  of  treatment,  and  antitumor  necrosis  factor  agents  are  safe,  efficacious,  and  effective.