RT Book, Section
A1 Liu, Frank
A1 Mehta, Ravindra
A2 Lerma, Edgar V.
A2 Berns, Jeffrey S.
A2 Nissenson, Allen R.
SR Print(0)
ID 6340650
T1 Chapter 52. Continuous Renal Replacement Therapy
T2 CURRENT Diagnosis & Treatment: Nephrology & Hypertension
YR 2009
FD 2009
PB The McGraw-Hill Companies
PP New York, NY
SN 978-0-07-144787-4
LK accessmedicine.mhmedical.com/content.aspx?aid=6340650
RD 2024/04/20
AB Continuous  renal  replacement  therapy  (CRRT)  represents  a  number  of  technically  distinct  modalities  characterized  by  slow  per-minute  solute  clearance  and  ultrafiltration  rates  that  are  spread  over  most  or  all  of  the  day  to  minimize  wide  metabolic  or  volume  shifts.  Continuous  techniques  were  originally  described  in  the  1970s  as  experimental  treatment  for  diuretic-resistant,  hypervolemic  patients  whose  clinical  picture  made  them  inappropriate  candidates  for  either  peritoneal  dialysis  (PD)  or  intermittent  hemodialysis  (IHD).  Since  then,  the  presence  of  CRRT  in  the  intensive  care  unit  (ICU)  has  evolved  both  in  scope  and  complexity,  and  as  a  result,  CRRT  techniques  are  quickly  becoming  the  standard  of  care  for  critically  ill  patients  with  acute  renal  failure  (ARF).  This  chapter  will  review  the  major  terms  used  in  the  delivery  of  CRRT,  the  most  prominent  clinical  and  technical  issues  encountered  by  the  healthcare  teams,  and  promising  technologies  that  may  improve  the  efficacy  and  future  applicability  of  the  relevant  modalities.