RT Book, Section
A1 Rocco, Michael V.
A1 Moossavi, Shahriar
A2 Lerma, Edgar V.
A2 Berns, Jeffrey S.
A2 Nissenson, Allen R.
SR Print(0)
ID 6340414
T1 Chapter 50. Hemodialysis
T2 CURRENT Diagnosis & Treatment: Nephrology & Hypertension
YR 2009
FD 2009
PB The McGraw-Hill Companies
PP New York, NY
SN 978-0-07-144787-4
LK accessmedicine.mhmedical.com/content.aspx?aid=6340414
RD 2024/04/17
AB The  major  forces  responsible  for  solute  transport  across  the  membrane  are  diffusion  and  convection.  Diffusion  is  influenced  by  the  concentration  gradient  of  the  solute,  the  solute  characteristics  (eg,  molecular  weight  and  charge),  and  the  membrane  characteristics  (eg,  pore  size  and  number).  Removal  of  solutes  by  diffusion  is  enhanced  by  a  large  concentration  gradient,  small  solute  size,  and  a  membrane  with  a  large  surface  area  and  many  large  pores.  The  concentration  gradient  is  maximized  by  using  countercurrent  flow  of  blood  and  dialysate.