RT Book, Section A1 Qamar, Amir A. A2 Greenberger, Norton J. A2 Blumberg, Richard S. A2 Burakoff, Robert SR Print(0) ID 55961794 T1 Chapter 50. Liver Transplantation T2 CURRENT Diagnosis & Treatment: Gastroenterology, Hepatology, & Endoscopy, 2e YR 2012 FD 2012 PB The McGraw-Hill Companies PP New York, NY SN 978-0-07-176848-1 LK accessmedicine.mhmedical.com/content.aspx?aid=55961794 RD 2024/04/19 AB Hepatitis C and hepatocellular carcinoma are among the leading indications for liver transplantation in the United States.Thorough medical, psychiatric, and social evaluation is required prior to listing patients for transplantation.The Model for End-Stage Liver Disease (MELD) score is widely used for prioritizing patients on the transplant waiting list.Liver biopsy is needed to confirm the diagnosis of acute rejection, which is common and occurs in up to 60% of patients.Medical and surgical complications after transplantation can occur immediately or years later.Biliary strictures and leaks occur in 15% of patients after transplantation.Long-term immunosuppression, particularly with calcineurin inhibitors, is associated with an increased risk of renal failure.