RT Book, Section
A1 Greenberger, Norton J.
A2 Greenberger, Norton J.
A2 Blumberg, Richard S.
A2 Burakoff, Robert
SR Print(0)
ID 55961390
T1 Chapter 46. Hepatorenal Syndrome
T2 CURRENT Diagnosis & Treatment: Gastroenterology, Hepatology, & Endoscopy, 2e
YR 2012
FD 2012
PB The McGraw-Hill Companies
PP New York, NY
SN 978-0-07-176848-1
LK accessmedicine.mhmedical.com/content.aspx?aid=55961390
RD 2024/04/16
AB Type  1  hepatorenal  syndrome—rapid  and  progressive  impairment  of  renal  function  defined  by  doubling  of  the  initial  serum  creatinine  level  to  >2.5  mg/dL  or  50%  reduction  of  the  initial  24-hour  creatinine  clearance  to  1.5  mg/dL  that  does  not  meet  the  criteria  for  type  1.Frequent  precipitants  include  gastrointestinal  bleeding,  sepsis,  spontaneous  bacterial  peritonitis,  aggressive  diuresis  and  paracentesis,  nonsteroidal  anti-inflammatory  drugs  (NSAIDs),  and  intravenous  contrast  agents.Intravenous  albumin,  1.0  g/kg,  should  be  administered  on  the  first  day  of  diagnosis  of  hepatorenal  syndrome,  Type  1  followed  by  20–40  g/day.