RT Book, Section A1 Lee, Linda S. A1 Carr-Locke, David L. A2 Greenberger, Norton J. A2 Blumberg, Richard S. A2 Burakoff, Robert SR Print(0) ID 55959934 T1 Chapter 35. Endoscopic Retrograde Cholangiopancreatography (ERCP) T2 CURRENT Diagnosis & Treatment: Gastroenterology, Hepatology, & Endoscopy, 2e YR 2012 FD 2012 PB The McGraw-Hill Companies PP New York, NY SN 978-0-07-176848-1 LK accessmedicine.mhmedical.com/content.aspx?aid=55959934 RD 2023/09/23 AB Endoscopic retrograde cholangiopancreatography (ERCP) (Figure 35–1) is a combined endoscopic and fluoroscopic procedure that was introduced in the early 1970s to allow access to the biliary and pancreatic ductal systems and their openings at the major and minor duodenal papillae. ERCP has evolved from a purely diagnostic technique, performed by a few, into a complex set of procedures integrating diagnosis and therapy for a wide variety of pancreatobiliary disorders offered in all major medical centers. ERCP requires dedicated training in order to acquire the range of techniques that include endoscopic papillectomy, sphincter of Oddi manometry, biliary sphincterotomy, pancreatic sphincterotomy, stone removal, tissue sampling, placement of plastic and metallic stents, and drainage of pancreatic fluid collections. Although it has become a highly successful therapeutic modality, ERCP also carries an overall morbidity of 7% that includes pancreatitis (4%), hemorrhage (1%), cholangitis (1%), perforation (0.5%), and death (0.1%). With the advent of magnetic resonance cholangiopancreatography (MRCP) (Figure 35–2) which safely and noninvasively images the pancreatic and biliary tracts, the need for purely diagnostic ERCP has appropriately diminished considerably while the demands for therapy have grown.