RT Book, Section
A1 Greenberger, Norton J.
A2 Greenberger, Norton J.
A2 Blumberg, Richard S.
A2 Burakoff, Robert
SR Print(0)
ID 55956994
T1 Chapter 14. Eosinophilic Esophagitis
T2 CURRENT Diagnosis & Treatment: Gastroenterology, Hepatology, & Endoscopy, 2e
YR 2012
FD 2012
PB The McGraw-Hill Companies
PP New York, NY
SN 978-0-07-176848-1
LK accessmedicine.mhmedical.com/content.aspx?aid=55956994
RD 2021/04/14
AB In  adults,  a  major  symptom  is  recurrent  dysphagia,  often  with  food  impaction;  mean  duration  of  symptoms  before  treatment  is  4–6  years.Esophageal  biopsy  shows  dense  eosinophilic  infiltration  (≥20  eosinophils  per  high  power  field  [HPF]).Full  diagnostic  criteria  are  (1)  clinical  symptoms  of  esophageal  dysfunction;  (2)  increased  eosinophils  in  esophageal  mucosal  biopsies;  (3)  lack  of  sustained  response  to  high-dose  proton  pump  inhibition  treatment  or  normal  pH  monitoring  of  the  distal  esophagus.