RT Book, Section A1 Zhu, Zhenglun A2 Greenberger, Norton J. A2 Blumberg, Richard S. A2 Burakoff, Robert SR Print(0) ID 55956443 T1 Chapter 10. Gastrointestinal Manifestations of Immunodeficiency T2 CURRENT Diagnosis & Treatment: Gastroenterology, Hepatology, & Endoscopy, 2e YR 2012 FD 2012 PB The McGraw-Hill Companies PP New York, NY SN 978-0-07-176848-1 LK accessmedicine.mhmedical.com/content.aspx?aid=55956443 RD 2024/03/28 AB Recurrent infections and diarrhea are the most common gastrointestinal manifestations of immunodeficiency.Some pathogens (eg, Mycobacterium avium complex), are unique to immunocompromised hosts; others (eg, Cryptosporidium, Giardia lamblia) cause self-limited diarrhea in healthy hosts but chronic diarrhea in immunosuppressed patients.In patients without a specific diagnosis after routine study, endoscopic evaluation with biopsy is important in establishing the diagnosis.Candida species, herpes simplex virus, cytomegalovirus, and Mycobacterium species are the most frequent causative agents of infectious esophagitis in an immunocompromised host.In immunocompromised patients, opportunistic infections are a major cause of abdominal pain and can evolve rapidly.The frequency of intestinal lymphomas is increased in patients with common variable immunodeficiency.