RT Book, Section A1 Hinckley, Jesse A1 Costello, Clifford A1 Kaul, Paritosh A1 Straub, Diane A2 Bunik, Maya A2 Levin, Myron J. A2 Abzug, Mark J. A2 Schreiner, Teri L. SR Print(0) ID 1211974996 T1 Adolescent Substance Use Disorders T2 Current Diagnosis & Treatment: Pediatrics, 27th Edition YR 2025 FD 2025 PB McGraw Hill PP New York, NY SN 9781265739898 LK accessmedicine.mhmedical.com/content.aspx?aid=1211974996 RD 2025/04/27 AB Adolescence is a vital period of neurodevelopment, and youth are particularly vulnerable to the neurodevelopmental consequences of substance use problems. Adolescence is also a time when many youth experiment with substance use, and more than 90% of individuals with substance use disorders (SUDs) started using substances by the age of 18 years. While most adolescents who experiment with substance use do not develop an SUD, many youth with frequent use do experience substance use problems, recently conceptualized as preaddiction by McLellan et al.