RT Book, Section A1 Kiefer, Todd A2 Papadakis, Maxine A. A2 McPhee, Stephen J. A2 Rabow, Michael W. A2 McQuaid, Kenneth R. A2 Gandhi, Monica SR Print(0) ID 1206531300 T1 Ventricular Septal Defect T2 Current Medical Diagnosis & Treatment 2024 YR 2024 FD 2024 PB McGraw-Hill Education PP New York, NY SN 9781265556037 LK accessmedicine.mhmedical.com/content.aspx?aid=1206531300 RD 2024/10/12 AB ESSENTIALS OF DIAGNOSISA restrictive VSD is small and makes a louder murmur than an unrestricted one, often with an accompanying thrill. The higher the gradient across the septum, the smaller the left-to-right shunt.Small defects may be asymptomatic.Larger defects result in pulmonary hypertension (Eisenmenger physiology) if not repaired or if the pulmonary circuit is not protected by RV outflow tract obstruction.Echocardiography/Doppler is diagnostic.