RT Book, Section A1 Rose, Stacey R. A1 Hamill, Richard J. A2 Papadakis, Maxine A. A2 McPhee, Stephen J. A2 Rabow, Michael W. A2 McQuaid, Kenneth R. A2 Gandhi, Monica SR Print(0) ID 1202072633 T1 Overview: Mycotic Infections T2 Current Medical Diagnosis & Treatment 2024 YR 2024 FD 2024 PB McGraw-Hill Education PP New York, NY SN 9781265556037 LK accessmedicine.mhmedical.com/content.aspx?aid=1202072633 RD 2024/11/11 AB Fungal infections are increasingly recognized as the use of broad-spectrum antimicrobial agents has expanded and the number of patients with immune deficiency or on immune modulators has grown. Some pathogens (eg, Cryptococcus, Pneumocystis, Fusarium) rarely cause serious disease in immunocompetent hosts. Other endemic fungi (eg, Histoplasma, Coccidioides, Paracoccidioides) commonly cause disease in immunocompetent persons but tend to be more aggressive in immunocompromised ones. Superficial mycoses are discussed in Chapter 6. Successful management of most systemic fungal infections requires knowledge of the natural history of these diseases and the specific tests needed to make a diagnosis as well as familiarity with the unique pharmacokinetics, adverse effects, and drug interactions of the various therapeutic agents. Consequently, clinicians with extensive experience in the management of fungal infections should be routinely consulted.