RT Book, Section A1 Friedman, Lawrence S. A2 Papadakis, Maxine A. A2 McPhee, Stephen J. A2 Rabow, Michael W. A2 McQuaid, Kenneth R. A2 Gandhi, Monica SR Print(0) ID 1202068492 T1 Acute Pancreatitis T2 Current Medical Diagnosis & Treatment 2024 YR 2024 FD 2024 PB McGraw-Hill Education PP New York, NY SN 9781265556037 LK accessmedicine.mhmedical.com/content.aspx?aid=1202068492 RD 2024/09/12 AB Key Clinical Updates in Acute PancreatitisGoal-directed therapy with moderate fluid resuscitation (a bolus of 10 mL/kg in patients with signs of hypovolemia followed by no more than 1.5 mL/kg/hour) may reduce the frequency of systemic inflammatory response syndrome and organ failure in this group of patients and appears to have the greatest benefit in patients with acute pancreatitis predicted to be mild in severity when started within 4 hours of the patient’s arrival at the hospital.de-Madaria E et al. N Engl J Med. [PMID: 36103415]