RT Book, Section A1 Prendergast, Niall T. A1 Girard, Timothy D. A1 Brummel, Nathan E. A2 Grippi, Michael A. A2 Antin-Ozerkis, Danielle E. A2 Dela Cruz, Charles S. A2 Kotloff, Robert M. A2 Kotton, Camille Nelson A2 Pack, Allan I. SR Print(0) ID 1195018768 T1 Diagnosis and Treatment of Pain, Agitation, and Delirium in the Intensive Care Unit T2 Fishman’s Pulmonary Diseases and Disorders, 6e YR 2023 FD 2023 PB McGraw-Hill Education PP New York, NY SN 9781260473988 LK accessmedicine.mhmedical.com/content.aspx?aid=1195018768 RD 2024/04/19 AB Most patients in intensive care units (ICUs) experience pain, agitation, or delirium at some point during their critical illness. During the last two decades, tremendous growth in knowledge regarding the assessment and management of these syndromes in the ICU has prompted important changes in the practice of intensive care medicine. Validated tools now allow clinicians to quickly and reliably evaluate patients for pain, assess their level of consciousness, and detect delirium. These assessments, in turn, guide clinicians as they choose and titrate therapies targeted to best manage a patient’s symptoms. Novel strategies to address pain, agitation, and delirium have recently been investigated. The use of validated tools to diagnose these important clinical syndromes and the use of evidence-based management strategies improve both short- and long-term outcomes. This chapter reviews these assessment tools and describes best practices for management of pain, agitation, and delirium in patients with critical illness.