RT Book, Section
A1 Albin, John S.
A1 Hurtado, Rocio M.
A2 Grippi, Michael A.
A2 Antin-Ozerkis, Danielle E.
A2 Dela Cruz, Charles S.
A2 Kotloff, Robert M.
A2 Kotton, Camille Nelson
A2 Pack, Allan I.
SR Print(0)
ID 1195015460
T1 Pulmonary Diseases Due to Nontuberculous Mycobacteria
T2 Fishman’s Pulmonary Diseases and Disorders, 6e
YR 2023
FD 2023
PB McGraw-Hill Education
PP New York, NY
SN 9781260473988
LK accessmedicine.mhmedical.com/content.aspx?aid=1195015460
RD 2025/03/24
AB This  chapter  focuses  on  the  diagnosis  and  management  of  pulmonary  infections  caused  by  nontuberculous  mycobacteria  (NTM),  a  large  group  of  species  of  the  genus  Mycobacterium  that  can  cause  disease  in  humans  and  that  are  distinct  from  other  classic  mycobacterial  pathogens,  such  as  M.  leprae,  M.  ulcerans,  and  species  of  the  M.  tuberculosis  complex.  Despite  the  diversity  of  this  group  of  pathogens,  the  clinical  presentation  and  diagnostic  approach  to  most  pulmonary  NTM  infections  is  similar,  and  the  vast  majority  of  disease  is  caused  by  a  handful  of  species,  including  those  of  the  M.  avium  (MAC)  and  M.  abscessus  (MAb)  complexes,  as  well  as  M.  kansasii  and  M.  xenopi.  Management  differs  according  to  species,  extent  of  disease,  and  susceptibility  patterns.  We  describe  here  the  epidemiology  and  pathogenesis  of  pulmonary  NTM  infections  and  a  general  diagnostic  approach.  We  then  proceed  to  the  treatment  regimens  used  for  common  NTMs  and  discuss  the  nuances  associated  with  management  in  special  populations.