RT Book, Section A1 Gurubhagavatula, Indira A1 Patil, Susheel P. A2 Grippi, Michael A. A2 Antin-Ozerkis, Danielle E. A2 Dela Cruz, Charles S. A2 Kotloff, Robert M. A2 Kotton, Camille Nelson A2 Pack, Allan I. SR Print(0) ID 1195011817 T1 Changes in the Cardiorespiratory System During Sleep T2 Fishman’s Pulmonary Diseases and Disorders, 6e YR 2023 FD 2023 PB McGraw-Hill Education PP New York, NY SN 9781260473988 LK accessmedicine.mhmedical.com/content.aspx?aid=1195011817 RD 2024/04/19 AB As outlined in Chapter 12, sleep occurs in distinct states classified broadly as non–rapid eye movement (NREM) sleep and rapid eye movement (REM) sleep. These states occur in a temporally organized fashion across the sleep period, with NREM dominating during the initial hours of sleep and REM during the later hours of sleep. REM sleep cycles occur in 90- to 120-min cycles, with a typical healthy adult experiencing 3 to 5 cycles during the major sleep bout. Specific alterations in autonomic regulation occur during REM sleep, which may at least partly explain the higher frequency of occurrence of myocardial infarction and ischemic stroke during early morning hours,1–3 when REM sleep predominates. This chapter presents additional information on alterations in cardiopulmonary function during sleep.