RT Book, Section A1 Jolly, Austin J. A1 Schwartz, David A. A2 Grippi, Michael A. A2 Antin-Ozerkis, Danielle E. A2 Dela Cruz, Charles S. A2 Kotloff, Robert M. A2 Kotton, Camille Nelson A2 Pack, Allan I. SR Print(0) ID 1195010495 T1 Acute and Chronic Responses to Toxic Inhalations T2 Fishman’s Pulmonary Diseases and Disorders, 6e YR 2023 FD 2023 PB McGraw-Hill Education PP New York, NY SN 9781260473988 LK accessmedicine.mhmedical.com/content.aspx?aid=1195010495 RD 2024/03/29 AB The lungs and airways are in constant contact with the outside world and are especially vulnerable to toxic substances present in the environment. Within seconds of exposure to an inhaled toxin, pathologic events occur that may cause immediate distress, produce illness lasting days, or even lead to the development of chronic lung disease. In this chapter we discuss the pathology and pathophysiology that can result from various inhaled toxins and highlight the role of several common and medically significant toxic inhalants that are known to cause acute and chronic pathophysiologic responses in the lung. We also describe several systemic syndromes caused by acute toxic inhalations. The scope of this chapter does not include chronic exposure to low levels of toxins.