RT Book, Section A1 Mathur, Aditi A1 Antin-Ozerkis, Danielle E. A2 Grippi, Michael A. A2 Antin-Ozerkis, Danielle E. A2 Dela Cruz, Charles S. A2 Kotloff, Robert M. A2 Kotton, Camille Nelson A2 Pack, Allan I. SR Print(0) ID 1195005403 T1 Interstitial Lung Disease: A Clinical Overview and General Approach T2 Fishman’s Pulmonary Diseases and Disorders, 6e YR 2023 FD 2023 PB McGraw-Hill Education PP New York, NY SN 9781260473988 LK accessmedicine.mhmedical.com/content.aspx?aid=1195005403 RD 2024/04/24 AB Interstitial lung disease (ILD) refers to a heterogenous collection of lung disorders that are grouped together because they share clinical, radiographic, and pathologic features. ILD is also referred to as diffuse parenchymal lung disease (DPLD) to clarify that the interstitium is not the only compartment of the lung affected. For example, organizing pneumonia and pulmonary alveolar proteinosis are alveolar filling processes, whereas respiratory bronchiolitis and chronic hypersensitivity pneumonitis may center on the airway. Occasionally, purely airway-centered disease like bronchiolitis obliterans may be initially identified as an ILD because of overlapping radiographic features. A structured approach is necessary since prognosis and therapy vary considerably depending on the diagnosis. While many ILDs are extremely rare, there are some, such as idiopathic pulmonary fibrosis (IPF) and sarcoidosis, that are seen commonly in general pulmonary practice.