RT Book, Section
A1 Chupp, Geoffrey L.
A1 Bell, Matthew C.
A1 Busse, William W.
A2 Grippi, Michael A.
A2 Antin-Ozerkis, Danielle E.
A2 Dela Cruz, Charles S.
A2 Kotloff, Robert M.
A2 Kotton, Camille Nelson
A2 Pack, Allan I.
SR Print(0)
ID 1194950625
T1 The Biology of Asthma
T2 Fishman’s Pulmonary Diseases and Disorders, 6e
YR 2023
FD 2023
PB McGraw-Hill Education
PP New York, NY
SN 9781260473988
LK accessmedicine.mhmedical.com/content.aspx?aid=1194950625
RD 2025/03/24
AB Asthma  is  a  chronic  inflammatory  disease  of  the  airways  characterized  by  persistent  variable  symptoms  that  include  shortness  of  breath,  cough,  and  wheezing.1  It  is  the  most  common  chronic  lung  disease  and  one  of  the  most  prevalent  diseases  in  the  United  States,  affecting  more  than  20  million  adults  and  7  million  children.2  Attempts  to  elucidate  the  cellular  and  molecular  effector  pathways  that  contribute  to  asthma  have  led  to  the  realization  that  it  is  a  protean  disease  driven  by  many  cell  types  and  mechanisms.  This  degree  of  mechanistic  variation  explains  the  numerous  clinical  phenotypes  that  are  now  recognized,  as  well  as  differences  in  response  to  treatment  with  inhaled  therapies  and  the  targeted  biologic  treatments  that  have  entered  the  clinic  over  the  last  decade.