RT Book, Section A1 Baldassarri, Stephen R. A1 Rennard, Stephen I. A2 Grippi, Michael A. A2 Antin-Ozerkis, Danielle E. A2 Dela Cruz, Charles S. A2 Kotloff, Robert M. A2 Kotton, Camille Nelson A2 Pack, Allan I. SR Print(0) ID 1194950438 T1 Cigarette Smoking, Smoking Cessation, and Electronic Cigarettes T2 Fishman’s Pulmonary Diseases and Disorders, 6e YR 2023 FD 2023 PB McGraw-Hill Education PP New York, NY SN 9781260473988 LK accessmedicine.mhmedical.com/content.aspx?aid=1194950438 RD 2024/04/19 AB Native Americans discovered the use of the tobacco plant, Nicotiana tabacum, during antiquity. By the time Columbus arrived in America, tobacco use was widespread throughout the Western Hemisphere and was well integrated into Native American cultures. Production of tobacco and its trade represented a major economic activity in the pre-Columbian Americas. Early European explorers learned of the tobacco plant from Native Americans, and by the mid-17th century tobacco was widely used in Europe.