RT Book, Section A1 Schulman, Edward S. A1 Sporn, Peter H.S. A1 Samarasinghe, Amali E. A2 Grippi, Michael A. A2 Antin-Ozerkis, Danielle E. A2 Dela Cruz, Charles S. A2 Kotloff, Robert M. A2 Kotton, Camille Nelson A2 Pack, Allan I. SR Print(0) ID 1194947186 T1 Mast Cells and Eosinophils T2 Fishman’s Pulmonary Diseases and Disorders, 6e YR 2023 FD 2023 PB McGraw-Hill Education PP New York, NY SN 9781260473988 LK accessmedicine.mhmedical.com/content.aspx?aid=1194947186 RD 2024/04/20 AB Hematopoietic stem cells that differentiate into common myeloid stem cells give rise to granulocytes that include mast cells (MC), eosinophils, basophils, and neutrophils. In addition to the shared heritage, granulocytes share physical and functional similarities. MCs and eosinophils are popularly known for their presence and function during allergic diseases. Because physicians have noted a clear connection between mast cell activation and the subsequent appearance of eosinophils both within the circulation and in tissues for over a century, MCs and eosinophils are considered together in this chapter.