RT Book, Section A1 MacDougall, Conan A2 Brunton, Laurence L. A2 Knollmann, Björn C. SR Print(0) ID 1193238656 T1 General Principles of Antimicrobial Therapy T2 Goodman & Gilman's: The Pharmacological Basis of Therapeutics, 14th Edition YR 2023 FD 2023 PB McGraw-Hill Education PP New York, NY SN 9781264258079 LK accessmedicine.mhmedical.com/content.aspx?aid=1193238656 RD 2024/04/24 AB AbbreviationsABC: ATP binding cassetteAUC: area under the Cp-time curveCCR5: chemokine receptor type 5CD4: T-helper cellsCMV: cytomegalovirusCp: plasma concentrationCPmax: peak plasma concentrationCYP: cytochrome P450DHFR: dihydrofolate reductaseDHPS: dihydropteroate synthaseE: effectEC: effective concentrationELF: epithelial lining fluidEmax: maximal effectHIV: human immunodeficiency virusIC: inhibitory concentrationMALDI-TOF MS: matrix-assisted laser desorption/ionization time-of-flight mass spectrometryMEC: minimum effective concentrationMIC: minimum inhibitory concentrationPAE: postantibiotic effectPCR: polymerase chain reactionPK/PD: pharmacokinetics-pharmacodynamicsPrEP: preexposure prophylaxisrpoB: RNA polymerase