RT Book, Section A1 Sharkey, Keith A. A1 MacNaughton, Wallace K. A2 Brunton, Laurence L. A2 Knollmann, Björn C. SR Print(0) ID 1193238429 T1 Gastrointestinal Motility and Water Flux, Emesis, and Biliary and Pancreatic Disease T2 Goodman & Gilman's: The Pharmacological Basis of Therapeutics, 14th Edition YR 2023 FD 2023 PB McGraw-Hill Education PP New York, NY SN 9781264258079 LK accessmedicine.mhmedical.com/content.aspx?aid=1193238429 RD 2024/03/28 AB AbbreviationsACh: acetylcholineANS: autonomic nervous systemCCK: cholecystokininCFTR: cystic fibrosis transmembrane conductance regulatorCTZ: chemoreceptor trigger zoneCYP: cytochrome P450DOR: delta opioid receptorECG: electrocardiogramENaC: epithelial sodium channelENS: enteric nervous systemFDA: U.S. Food and Drug AdministrationGC: guanyl cyclaseGERD: gastroesophageal reflux diseaseGI: gastrointestinalGLP: glucagon-like peptideGPCR: G protein-coupled receptorHIV: human immunodeficiency virus5HT: serotonin, 5-hydroxytryptamineIBS: irritable bowel syndromeKOR: kappa opioid receptorMOR: mu opioid receptorNEP: neutral endopeptidaseNHE: Na+-H+ exchangerNK: neurokininNO: nitric oxideNTS: nucleus of the solitary tractOTC: over-the-counterPEG: polyethylene glycolPgp: P-glycoprotein (MDR1, ABCB1)PK: protein kinase (e.g., PKA, PKC)PONV: postoperative nausea and vomitingQT: ECG interval (duration of ventricular depolarization and repolarization)SLC: solute carrier transporterSSRI: selective serotonin reuptake inhibitorSST: somatostatinTMEM: transmembrane proteinUSP: U.S. PharmacopeiaVIP: vasoactive intestinal peptide