RT Book, Section A1 Kiefer, Todd A1 Granger, Christopher B. A1 Jackson, Kevin P. A2 Papadakis, Maxine A. A2 McPhee, Stephen J. A2 Rabow, Michael W. A2 McQuaid, Kenneth R. SR Print(0) ID 1193146914 T1 Ventricular Septal Defect T2 Current Medical Diagnosis & Treatment 2023 YR 2023 FD 2023 PB McGraw-Hill Education PP New York, NY SN 9781264687343 LK accessmedicine.mhmedical.com/content.aspx?aid=1193146914 RD 2024/04/18 AB ESSENTIALS OF DIAGNOSISA restrictive VSD is small and makes a louder murmur than an unrestricted one, often with an accompanying thrill. The higher the gradient across the septum, the smaller the left-to-right shunt.Small defects may be asymptomatic.Larger defects result in pulmonary hypertension (Eisenmenger physiology) if not repaired or if the pulmonary circuit is not protected by RV outflow tract obstruction.Echocardiography/Doppler is diagnostic.