RT Book, Section A1 Kiefer, Todd A1 Granger, Christopher B. A1 Jackson, Kevin P. A2 Papadakis, Maxine A. A2 McPhee, Stephen J. A2 Rabow, Michael W. A2 McQuaid, Kenneth R. SR Print(0) ID 1193146889 T1 Atrial Septal Defect & Patent Foramen Ovale T2 Current Medical Diagnosis & Treatment 2023 YR 2023 FD 2023 PB McGraw-Hill Education PP New York, NY SN 9781264687343 LK accessmedicine.mhmedical.com/content.aspx?aid=1193146889 RD 2023/12/02 AB ESSENTIALS OF DIAGNOSISOften asymptomatic and discovered on routine physical examination.With an ASD and left-to-right shunt: RV lift; S2 widely split and fixed.Echocardiography/Doppler is diagnostic.ASDs should be closed if there is evidence of an RV volume overload regardless of symptoms.A PFO, present in 25% of the population, rarely can lead to paradoxical emboli. Suspicion should be highest in patients who have cryptogenic stroke before age 55 years.