RT Book, Section
A1 Rogers, Vanessa L.
A1 Roberts, Scott W.
A2 Papadakis, Maxine A.
A2 McPhee, Stephen J.
A2 Rabow, Michael W.
A2 McQuaid, Kenneth R.
SR Print(0)
ID 1193159382
T1 Preterm Labor
T2 Current Medical Diagnosis & Treatment 2023
YR 2023
FD 2023
PB McGraw-Hill Education
PP New York, NY
SN 9781264687343
LK accessmedicine.mhmedical.com/content.aspx?aid=1193159382
RD 2024/04/25
AB Key  Clinical  Updates  in  Preterm  LaborThe  recommended  regimen  for  antimicrobial  prophylaxis  against  group  B  streptococcus  is  penicillin  G,  5  million  units  intravenously  as  a  loading  dose  and  then  2.5–3  million  units  intravenously  every  4  hours  until  delivery.  In  penicillin-allergic  patients  not  at  high  risk  for  anaphylaxis,  2  g  of  cefazolin  can  be  given  intravenously  as  an  initial  dose  and  then  1  g  intravenously  every  8  hours  until  delivery.  In  patients  at  high  risk  for  anaphylaxis,  vancomycin,  20  mg/kg  intravenously  every  8  hours  until  delivery,  can  be  used.  Clindamycin,  900  mg  intravenously  every  8  hours  until  delivery,  can  also  be  used  after  a  group  B  streptococcal  isolate  has  been  confirmed  to  be  susceptible  to  clindamycin.American  College  of  Obstetricians  and  Gynecologists.  Obstet  Gynecol.  [PMID:  34794160]