RT Book, Section
A1 Smollin, Craig
A2 Papadakis, Maxine A.
A2 McPhee, Stephen J.
A2 Rabow, Michael W.
A2 McQuaid, Kenneth R.
SR Print(0)
ID 1193161678
T1 Cyanide Poisoning
T2 Current Medical Diagnosis & Treatment 2023
YR 2023
FD 2023
PB McGraw-Hill Education
PP New York, NY
SN 9781264687343
LK accessmedicine.mhmedical.com/content.aspx?aid=1193161678
RD 2024/04/19
AB Cyanide  is  a  highly  toxic  chemical  used  widely  in  research  and  commercial  laboratories  and  many  industries.  Its  gaseous  form,  hydrogen  cyanide,  is  an  important  component  of  smoke  in  fires.  Cyanide-generating  glycosides  are  also  found  in  the  pits  of  apricots  and  other  related  plants.  Cyanide  is  generated  by  the  breakdown  of  nitroprusside,  and  poisoning  can  result  from  rapid  high-dose  infusions.  Cyanide  is  also  formed  by  metabolism  of  acetonitrile,  a  solvent  found  in  some  over-the-counter  fingernail  glue  removers.  Cyanide  is  rapidly  absorbed  by  inhalation,  skin  absorption,  or  ingestion.  It  disrupts  cellular  function  by  inhibiting  cytochrome  oxidase  and  preventing  cellular  oxygen  utilization.