RT Book, Section A1 Smollin, Craig A2 Papadakis, Maxine A. A2 McPhee, Stephen J. A2 Rabow, Michael W. A2 McQuaid, Kenneth R. SR Print(0) ID 1193161655 T1 Chlorinated Insecticides Posioning T2 Current Medical Diagnosis & Treatment 2023 YR 2023 FD 2023 PB McGraw-Hill Education PP New York, NY SN 9781264687343 LK accessmedicine.mhmedical.com/content.aspx?aid=1193161655 RD 2024/04/25 AB Lindane (Kwell) and other chlorinated insecticides (chlorophenothane [DDT], lindane, toxaphene, chlordane, aldrin, endrin) are CNS stimulants that can cause poisoning by ingestion, inhalation, or direct contact. Most of these agents have been removed from the United States market because of their acute toxicity and their potential to accumulate in the food chain. The estimated lethal dose is about 20 g for DDT, 3 g for lindane, 2 g for toxaphene, 1 g for chlordane, and less than 1 g for endrin and aldrin. The manifestations of poisoning are nervous irritability, muscle twitching, seizures, and coma. Arrhythmias may occur. Liver and kidney damage are reported.