RT Book, Section
A1 Smollin, Craig
A2 Papadakis, Maxine A.
A2 McPhee, Stephen J.
A2 Rabow, Michael W.
A2 McQuaid, Kenneth R.
SR Print(0)
ID 1193161640
T1 Chemical Warfare: Nerve Agents
T2 Current Medical Diagnosis & Treatment 2023
YR 2023
FD 2023
PB McGraw-Hill Education
PP New York, NY
SN 9781264687343
LK accessmedicine.mhmedical.com/content.aspx?aid=1193161640
RD 2024/04/24
AB Nerve  agents  used  in  chemical  warfare  work  by  cholinesterase  inhibition  and  are  most  commonly  organophosphorus  compounds.  Agents  such  as  tabun  (GA),  sarin  (GB),  soman  (GD),  VX,  and  a  group  of  compounds  known  as  novichoks  are  similar  to  insecticides  such  as  malathion  but  are  vastly  more  potent.  They  may  be  inhaled  or  absorbed  through  the  skin.  Systemic  effects  due  to  unopposed  action  of  acetylcholine  include  miosis,  salivation,  abdominal  cramps,  diarrhea,  and  muscle  paralysis  producing  respiratory  arrest.  Inhalation  also  produces  severe  bronchoconstriction  and  copious  nasal  and  tracheobronchial  secretions.