RT Book, Section A1 Friedman, Lawrence S. A2 Papadakis, Maxine A. A2 McPhee, Stephen J. A2 Rabow, Michael W. A2 McQuaid, Kenneth R. SR Print(0) ID 1193152539 T1 Cirrhosis T2 Current Medical Diagnosis & Treatment 2023 YR 2023 FD 2023 PB McGraw-Hill Education PP New York, NY SN 9781264687343 LK accessmedicine.mhmedical.com/content.aspx?aid=1193152539 RD 2024/04/19 AB Key Clinical Updates in CirrhosisIn patients with clinically significant portal hypertension, carvedilol, a nonselective beta receptor antagonist with alpha-1 blocking activity, appears to reduce the frequency of decompensating events, although it may lead to hypotension particularly in patients with decompensated cirrhosis.Tandon P et al. Clin Gastroenterol Hepatol. [PMID: 33221550]Vancomycin should be added in patients with prior bacterial peritonitis or a positive surveillance swab for methicillin-resistant Staphylococcus aureus. Daptomycin should be added in patients with a positive surveillance swab for vancomycin-resistant enterococcus. Meropenem can be used in patients with current or recent exposure to piperacillin-tazobactam.Biggins SW et al. Hepatology. [PMID: 33942342]