RT Book, Section A1 Shinkai, Kanade A1 Fox, Lindy P. A2 Papadakis, Maxine A. A2 McPhee, Stephen J. A2 Rabow, Michael W. A2 McQuaid, Kenneth R. SR Print(0) ID 1193628994 T1 Pruritus T2 Current Medical Diagnosis & Treatment 2023 YR 2023 FD 2023 PB McGraw-Hill Education PP New York, NY SN 9781264687343 LK accessmedicine.mhmedical.com/content.aspx?aid=1193628994 RD 2024/10/15 AB Pruritus is the sensation that provokes a desire to scratch1. Pruritus as a medical complaint is 40% as common as low back pain. Elderly Asian men are most significantly affected, with 20% of all health care visits in Asian men over the age of 65 involving the complaint of itch. The quality of life of a patient with chronic pruritus is the same as a patient undergoing hemodialysis. Better understanding of the role of pruritogens (interleukins-31, -4, -13 and thymic stromal lymphopoietin) in the pathophysiology of itch has enabled recent therapeutic advances.