RT Book, Section A1 Fitzgerald, Paul A. A2 Papadakis, Maxine A. A2 McPhee, Stephen J. A2 Rabow, Michael W. A2 McQuaid, Kenneth R. SR Print(0) ID 1193160621 T1 Rickets & Osteomalacia T2 Current Medical Diagnosis & Treatment 2023 YR 2023 FD 2023 PB McGraw-Hill Education PP New York, NY SN 9781264687343 LK accessmedicine.mhmedical.com/content.aspx?aid=1193160621 RD 2024/04/19 AB ESSENTIALS OF DIAGNOSISLow bone density from defective mineralization.Caused by deficiency in calcium, phosphorus, or low alkaline phosphatase.Rickets: defective bone mineralization in childhood or adolescence before epiphyseal fusion.Osteomalacia: defective bone mineralization in adults with fused epiphyses.Painful proximal muscle weakness (especially pelvic girdle); bone pain.Low serum 25-hydroxy-vitamin D (25-OHD), hypocalcemia, hypocalciuria, hypophosphatemia, secondary hyperparathyroidism.Classic radiologic features may be present.