RT Book, Section
A1 Philip, Susan S.
A2 Papadakis, Maxine A.
A2 McPhee, Stephen J.
A2 Rabow, Michael W.
A2 McQuaid, Kenneth R.
SR Print(0)
ID 1193137202
T1 Endemic Syphilis (Bejel)
T2 Current Medical Diagnosis & Treatment 2023
YR 2023
FD 2023
PB McGraw-Hill Education
PP New York, NY
SN 9781264687343
LK accessmedicine.mhmedical.com/content.aspx?aid=1193137202
RD 2024/04/19
AB Endemic  syphilis  is  an  acute  or  chronic  infection  caused  by  T  pallidum  subspecies  endemicum.  It  has  been  reported  in  several  countries,  particularly  in  the  eastern  Mediterranean  area  and  in  Southeast  Asia.  It  often  has  local  names:  bejel  in  Syria,  Saudi  Arabia,  and  Iraq;  and  dichuchwa,  njovera,  and  siti  in  Africa.  Moist  ulcerated  lesions  of  the  skin  or  oral  or  nasopharyngeal  mucosa  are  the  most  common  manifestations.  Generalized  lymphadenopathy  and  secondary  and  tertiary  bone  and  skin  lesions  are  also  common.  Deep  leg  pain  points  to  periostitis  or  osteomyelitis.  In  the  late  stages  of  disease,  destructive  gummatous  lesions  similar  to  those  seen  in  yaws  can  develop,  resulting  in  loss  of  cartilage  and  saber  shin  deformity.  Cardiovascular  and  CNS  involvement  are  rare.  See  above  for  therapy.