RT Book, Section
A1 Shinkai, Kanade
A1 Fox, Lindy P.
A2 Papadakis, Maxine A.
A2 McPhee, Stephen J.
A2 Rabow, Michael W.
A2 McQuaid, Kenneth R.
SR Print(0)
ID 1193156601
T1 Atypical Nevi
T2 Current Medical Diagnosis & Treatment 2023
YR 2023
FD 2023
PB McGraw-Hill Education
PP New York, NY
SN 9781264687343
LK accessmedicine.mhmedical.com/content.aspx?aid=1193156601
RD 2024/04/19
AB The  term  “atypical  nevus”  or  “atypical  mole”  has  supplanted  “dysplastic  nevus.”  The  diagnosis  of  atypical  moles  is  made  clinically,  not  histologically.  Moles  should  be  removed  only  if  they  are  suspected  to  be  melanomas.  Dermoscopy  by  a  trained  clinician  may  be  a  useful  tool  in  the  evaluation  of  atypical  nevi.  Clinically,  these  moles  are  large  (6  mm  or  more  in  diameter),  with  an  ill-defined,  irregular  border  and  irregularly  distributed  pigmentation  (Figure  6–2)  (eFigure  6–3).  An  estimated  5–10%  of  the  White  population  in  the  United  States  has  one  or  more  atypical  nevi,  for  which  recreational  sun  exposure  is  a  primary  risk  in  nonfamilial  settings.  There  is  an  increased  risk  of  melanoma  in  patients  with  50  or  more  nevi  with  one  or  more  atypical  moles  and  one  mole  8  mm  or  larger  and  patients  with  any  number  of  definitely  atypical  moles.  These  patients  should  be  educated  in  how  to  recognize  changes  in  moles  and  be  monitored  every  6–12  months  by  a  clinician.  Kindreds  with  familial  melanoma  (numerous  atypical  nevi  and  a  family  history  of  two  first-degree  relatives  with  melanoma)  require  closer  attention  since  their  risk  of  developing  single  or  multiple  melanomas  approaches  50%  by  age  50.