RT Book, Section A1 Philip, Susan S. A2 Papadakis, Maxine A. A2 McPhee, Stephen J. A2 Rabow, Michael W. A2 McQuaid, Kenneth R. SR Print(0) ID 1193137044 T1 Syphilis: Course & Prognosis T2 Current Medical Diagnosis & Treatment 2023 YR 2023 FD 2023 PB McGraw-Hill Education PP New York, NY SN 9781264687343 LK accessmedicine.mhmedical.com/content.aspx?aid=1193137044 RD 2024/04/19 AB The lesions associated with primary and secondary syphilis are self-limiting, even without treatment, and resolve with few or no residua. Ocular and otologic syphilis have been associated with permanent vision and hearing loss. Tertiary and congenital syphilis may be highly destructive and permanently disabling and may lead to death. While infection is rarely eradicated completely in the absence of treatment, most infections likely remain latent without sequelae, and only a small number of latent infections progress to further disease.