RT Book, Section A1 Dirkx, Tonja C. A1 Woodell, Tyler B. A2 Papadakis, Maxine A. A2 McPhee, Stephen J. A2 Rabow, Michael W. A2 McQuaid, Kenneth R. SR Print(0) ID 1193127768 T1 Nephrogenic Systemic Fibrosis T2 Current Medical Diagnosis & Treatment 2023 YR 2023 FD 2023 PB McGraw-Hill Education PP New York, NY SN 9781264687343 LK accessmedicine.mhmedical.com/content.aspx?aid=1193127768 RD 2024/09/18 AB Nephrogenic systemic fibrosis is a multisystem disorder seen exclusively in patients with advanced CKD (primarily with an eGFR less than 15 mL/minute/1.73 m2, but rarely 15–29 mL/minute/1.73 m2), AKI, and after kidney transplantation. Histopathologically, there is an increase in dermal spindle cells positive for CD34 and procollagen I. Collagen bundles with mucin and elastic fibers are also noted.