RT Book, Section A1 Boslett, Bryn A. A1 Bystritsky, Rachel A2 Papadakis, Maxine A. A2 McPhee, Stephen J. A2 Rabow, Michael W. A2 McQuaid, Kenneth R. SR Print(0) ID 1193136731 T1 Gastroenteritis Caused by Escherichia Coli T2 Current Medical Diagnosis & Treatment 2023 YR 2023 FD 2023 PB McGraw-Hill Education PP New York, NY SN 9781264687343 LK accessmedicine.mhmedical.com/content.aspx?aid=1193136731 RD 2024/09/18 AB E coli causes gastroenteritis by a variety of mechanisms. Enterotoxigenic E coli (ETEC) elaborates either a heat-stable or heat-labile toxin that mediates the disease. ETEC is an important cause of traveler’s diarrhea (see Chapter 30, Traveler’s Diarrhea). Enteroinvasive E coli (EIEC) differs from other E coli bowel pathogens in that these strains invade cells, causing bloody diarrhea and dysentery similar to infection with Shigella species. EIEC is uncommon in the United States. Neither ETEC nor EIEC strains are routinely isolated and identified from stool cultures because there is no selective medium but can be detected on stool-based multiplex-PCR. Antimicrobial therapy, such as ciprofloxacin 500 mg orally twice daily, shortens the clinical course, but the disease is self-limited.