RT Book, Section A1 Akamine, Christine A1 Clark, Eva A1 Shandera, Wayne X. A2 Papadakis, Maxine A. A2 McPhee, Stephen J. A2 Rabow, Michael W. A2 McQuaid, Kenneth R. SR Print(0) ID 1193272327 T1 Spotted Fevers T2 Current Medical Diagnosis & Treatment 2023 YR 2023 FD 2023 PB McGraw-Hill Education PP New York, NY SN 9781264687343 LK accessmedicine.mhmedical.com/content.aspx?aid=1193272327 RD 2024/09/19 AB ESSENTIALS OF DIAGNOSISExposure to tick bite in an endemic area.Influenza-like prodrome followed by fever, severe headache, and myalgias; occasionally, delirium and coma.Red macular rash appears between days 2 and 6 of fever, first on the wrists and ankles and then spreading centrally; it may become petechial.Mortality over 70% in untreated patients.Serial serologic examinations by indirect fluorescent antibody confirm the diagnosis retrospectively.