RT Book, Section A1 Akamine, Christine A1 Clark, Eva A1 Shandera, Wayne X. A2 Papadakis, Maxine A. A2 McPhee, Stephen J. A2 Rabow, Michael W. A2 McQuaid, Kenneth R. SR Print(0) ID 1193135883 T1 Adenovirus Infections T2 Current Medical Diagnosis & Treatment 2023 YR 2023 FD 2023 PB McGraw-Hill Education PP New York, NY SN 9781264687343 LK accessmedicine.mhmedical.com/content.aspx?aid=1193135883 RD 2024/10/15 AB At least 88 serotypes of adenovirus are currently described, and these are members of seven species classified A–G with species A-D showing most pathogenic types. About half of these subgroups produce a variety of clinical syndromes. Adenoviruses show a worldwide distribution and occur throughout the year. These infections are usually self-limited or clinically inapparent and occur most commonly among infants, young children, and military recruits and appear to be responsible for about 2–7% of childhood viral respiratory infections and 5–11% of viral pneumonia and bronchiolitis. These infections cause particular morbidity and mortality in immunocompromised persons, such as people living with HIV infection and COPD, as well as in patients who have undergone solid organ and hematopoietic stem cell transplantation or cardiac surgery or in those who have received cancer chemotherapy. A few cases of donor-transmitted adenoviral infection have been reported in past years.