RT Book, Section
A1 Akamine, Christine
A1 Clark, Eva
A1 Shandera, Wayne X.
A2 Papadakis, Maxine A.
A2 McPhee, Stephen J.
A2 Rabow, Michael W.
A2 McQuaid, Kenneth R.
SR Print(0)
ID 1193135883
T1 Adenovirus Infections
T2 Current Medical Diagnosis & Treatment 2023
YR 2023
FD 2023
PB McGraw-Hill Education
PP New York, NY
SN 9781264687343
LK accessmedicine.mhmedical.com/content.aspx?aid=1193135883
RD 2024/04/18
AB At  least  88  serotypes  of  adenovirus  are  currently  described,  and  these  are  members  of  seven  species  classified  A–G  with  species  A-D  showing  most  pathogenic  types.  About  half  of  these  subgroups  produce  a  variety  of  clinical  syndromes.  Adenoviruses  show  a  worldwide  distribution  and  occur  throughout  the  year.  These  infections  are  usually  self-limited  or  clinically  inapparent  and  occur  most  commonly  among  infants,  young  children,  and  military  recruits  and  appear  to  be  responsible  for  about  2–7%  of  childhood  viral  respiratory  infections  and  5–11%  of  viral  pneumonia  and  bronchiolitis.  These  infections  cause  particular  morbidity  and  mortality  in  immunocompromised  persons,  such  as  people  living  with  HIV  infection  and  COPD,  as  well  as  in  patients  who  have  undergone  solid  organ  and  hematopoietic  stem  cell  transplantation  or  cardiac  surgery  or  in  those  who  have  received  cancer  chemotherapy.  A  few  cases  of  donor-transmitted  adenoviral  infection  have  been  reported  in  past  years.