RT Book, Section A1 Manno, Rebecca L. A1 Yazdany, Jinoos A1 Tarrant, Teresa K. A1 Kwan, Mildred A2 Papadakis, Maxine A. A2 McPhee, Stephen J. A2 Rabow, Michael W. A2 McQuaid, Kenneth R. SR Print(0) ID 1193126187 T1 Allergy Testing T2 Current Medical Diagnosis & Treatment 2023 YR 2023 FD 2023 PB McGraw-Hill Education PP New York, NY SN 9781264687343 LK accessmedicine.mhmedical.com/content.aspx?aid=1193126187 RD 2024/04/19 AB To maximize the positive predictive value of allergy testing, a positive test result must correlate with patient history of immediate hypersensitivity, and the immune pathogenesis must be consistent with IgE-mediated disease. IgE antibodies are detected by allergen skin testing or serum IgE testing. These allergy tests are useful for patients with symptoms consistent with allergic disease (eg, rhinitis, asthma, or both), patients who may be eligible for allergen immunotherapy, and patients who have strong predisposing factors for atopy (eg, family history of atopy or ongoing exposure to potential sources of allergen). Patients with diseases that are not IgE-mediated or who do not demonstrate an immediate hypersensitivity reaction (eg, non-anaphylaxis food sensitivities or intolerances, allergies to some drugs, and allergic contact dermatitis) usually do not benefit from this type of testing.