RT Book, Section
A1 Manno, Rebecca L.
A1 Yazdany, Jinoos
A1 Tarrant, Teresa K.
A1 Kwan, Mildred
A2 Papadakis, Maxine A.
A2 McPhee, Stephen J.
A2 Rabow, Michael W.
A2 McQuaid, Kenneth R.
SR Print(0)
ID 1193125968
T1 Inflammatory Bowel Disease–Associated Spondyloarthritis
T2 Current Medical Diagnosis & Treatment 2023
YR 2023
FD 2023
PB McGraw-Hill Education
PP New York, NY
SN 9781264687343
LK accessmedicine.mhmedical.com/content.aspx?aid=1193125968
RD 2024/04/24
AB One-fifth  of  patients  with  IBD  have  arthritis,  which  complicates  Crohn  disease  somewhat  more  frequently  than  it  does  ulcerative  colitis.  In  both  diseases,  two  distinct  forms  of  arthritis  occur.  The  first  is  peripheral  arthritis—usually  a  nondeforming  asymmetric  oligoarthritis  of  large  joints—in  which  the  activity  of  the  joint  disease  parallels  that  of  the  bowel  disease.  The  arthritis  usually  begins  months  to  years  after  the  bowel  disease,  but  occasionally  the  joint  symptoms  develop  earlier  and  may  be  prominent  enough  to  cause  the  patient  to  overlook  intestinal  symptoms.  The  second  form  of  arthritis  is  a  spondylitis  that  is  indistinguishable  by  symptoms  or  radiographs  from  ankylosing  spondylitis  and  follows  a  course  independent  of  the  bowel  disease.  About  50%  of  these  patients  are  HLA-B27  positive.