RT Book, Section
A1 Papadakis, Maxine A.
A1 McPhee, Stephen J.
A1 Rabow, Michael W.
A1 McQuaid, Kenneth R.
SR Print(0)
ID 1193123618
T1 HIV Infection & AIDS Year in Review
T2 Current Medical Diagnosis & Treatment 2023
YR 2023
FD 2023
PB McGraw-Hill Education
PP New York, NY
SN 9781264687343
LK accessmedicine.mhmedical.com/content.aspx?aid=1193123618
RD 2024/04/18
AB In  the  ANCHOR  study,  which  involved  nearly  4500  individuals  with  anal  high-grade  squamous  intraepithelial  lesions  (HGSIL),  nine  patients  who  were  assigned  to  aggressive  therapy  (mostly  office-based  electrocautery)  developed  anal  cancer  compared  with  21  of  those  in  an  active  monitoring  group,  representing  a  57%  decrease  in  relative  risk  over  the  median  25.8-month  follow-up  period.  This  pivotal  study  will  change  care  toward  more  aggressive  screening  for  HGSIL  and  treatment  to  prevent  progression  to  anal  cancer.