RT Book, Section A1 Schultz, Brittney A1 Goldfarb, Noah A2 Soutor, Carol A2 Hordinsky, Maria K. SR Print(0) ID 1190940310 T1 Skin Diseases of the Feet T2 Clinical Dermatology: Diagnosis and Management of Common Disorders, 2e YR 2022 FD 2022 PB McGraw-Hill Education PP New York, NY SN 9781264257379 LK accessmedicine.mhmedical.com/content.aspx?aid=1190940310 RD 2024/04/24 AB Acral surfaces, such as the feet, have unique characteristics that make them prone to certain dermatologic conditions. The plantar surface of the foot has the thickest keratin layer, a high concentration of eccrine sweat glands as well as sensory nerves, Pacinian corpuscles and other mechanoreceptors. The combination of abundant keratin and sweat creates an ideal environment for fungal infections. Friction and contact with footwear also make the feet susceptible to contact dermatitis. In addition, the feet are disproportionately affected by vascular disorders, due to their gravity-dependent anatomical location, and by peripheral small fiber sensory neuropathies. Since the feet are a site of frequent injury, vascular disorders and sensory neuropathies predispose this area to recurrent and difficult to manage wounds.