RT Book, Section A1 Dimopoulos, Konstantinos A1 Constantine, Andrew A2 Fuster, Valentin A2 Narula, Jagat A2 Vaishnava, Prashant A2 Leon, Martin B. A2 Callans, David J. A2 Rumsfeld, John S. A2 Poppas, Athena SR Print(0) ID 1202452127 T1 Right-Sided Lesions T2 Fuster and Hurst's The Heart, 15e YR 2022 FD 2022 PB McGraw-Hill Education PP New York, NY SN 9781264257560 LK accessmedicine.mhmedical.com/content.aspx?aid=1202452127 RD 2024/04/18 AB Chapter SummaryThis chapter provides an overview of the foremost right-sided lesions affecting adults with congenital heart disease (see Fuster and Hurst’s Central Illustration), focusing on pathophysiology and clinical management. Right-sided cardiac lesions are typically congenital and include a wide spectrum of conditions of differing complexity. Even “simple” right-sided heart lesions can cause significant right ventricular pressure or volume overload, obstruction of flow to the lungs, and systemic venous congestion. More complex lesions, such as Tetralogy of Fallot, also consist of predominantly right-sided anatomic features and long-term residual right-sided lesions may be present after repair (eg, pulmonary regurgitation). Advances in diagnosis and timely surgical intervention have considerably improved the outlook of these lesions and have minimized long-term complications. However, adults with congenital heart disease remain at risk of long-term sequelae, such as exercise intolerance, right-sided heart failure, and arrhythmias. Long-term specialist care is, therefore, essential, even after successful surgical repair. Expert input and individualized advice are also required in special situations, including pregnancy, noncardiac surgery, and when determining the type and intensity of exercise or sports that patients can practice.