RT Book, Section
A1 Creager, Mark A.
A1 Loscalzo, Joseph
A2 Loscalzo, Joseph
A2 Fauci, Anthony
A2 Kasper, Dennis
A2 Hauser, Stephen
A2 Longo, Dan
A2 Jameson, J. Larry
SR Print(0)
ID 1198228615
T1 Arterial Diseases of the Extremities
T2 Harrison's Principles of Internal Medicine, 21e
YR 2022
FD 2022
PB McGraw-Hill Education
PP New York, NY
SN 9781264268504
LK accessmedicine.mhmedical.com/content.aspx?aid=1198228615
RD 2024/04/23
AB Peripheral  artery  disease  (PAD)  is  defined  as  a  clinical  disorder  in  which  there  is  a  stenosis  or  occlusion  in  the  aorta  or  the  arteries  of  the  limbs.  Atherosclerosis  is  the  leading  cause  of  PAD  in  patients  >40  years  old.  Other  causes  include  thrombosis,  embolism,  vasculitis,  fibromuscular  dysplasia,  entrapment,  cystic  adventitial  disease,  and  trauma.  The  highest  prevalence  of  atherosclerotic  PAD  occurs  in  the  sixth  and  seventh  decades  of  life.  As  in  patients  with  atherosclerosis  of  the  coronary  and  cerebral  vasculature,  there  is  an  increased  risk  of  developing  PAD  in  cigarette  smokers  and  in  persons  with  diabetes  mellitus,  hypercholesterolemia,  hypertension,  or  renal  insufficiency.