RT Book, Section A1 Smith, Wade S. A1 Johnston, S. Claiborne A1 Hemphill, III, J. Claude A2 Loscalzo, Joseph A2 Fauci, Anthony A2 Kasper, Dennis A2 Hauser, Stephen A2 Longo, Dan A2 Jameson, J. Larry SR Print(0) ID 1199142923 T1 Introduction to Cerebrovascular Diseases T2 Harrison's Principles of Internal Medicine, 21e YR 2022 FD 2022 PB McGraw-Hill Education PP New York, NY SN 9781264268504 LK accessmedicine.mhmedical.com/content.aspx?aid=1199142923 RD 2024/10/10 AB Cerebrovascular diseases include some of the most common and devastating disorders: ischemic stroke and hemorrhagic stroke. Stroke is the second leading cause of death worldwide, with 6.2 million dying from stroke in 2015, an increase of 830,000 since the year 2000. In 2016, the lifetime global risk of stroke from age 25 years onward was 25%, an increase of 8.9% from 1990. Nearly 7 million Americans age 20 or older report having had a stroke, and the prevalence is estimated to rise by 3.4 million adults in the next decade, representing 4% of the entire adult population. Conversely, case-specific disability-adjusted life-years due to stroke are falling, likely due to better prevention and treatment, but overall disease burden will continue to climb as the population ages, and stroke is likely to remain the second most common disabling condition in individuals aged 50 or older worldwide.