RT Book, Section
A1 Marrazzo, Jeanne M.
A1 Holmes, King K.
A2 Loscalzo, Joseph
A2 Fauci, Anthony
A2 Kasper, Dennis
A2 Hauser, Stephen
A2 Longo, Dan
A2 Jameson, J. Larry
SR Print(0)
ID 1198219690
T1 Sexually Transmitted Infections: Overview and Clinical Approach
T2 Harrison's Principles of Internal Medicine, 21e
YR 2022
FD 2022
PB McGraw-Hill Education
PP New York, NY
SN 9781264268504
LK accessmedicine.mhmedical.com/content.aspx?aid=1198219690
RD 2023/06/09
AB Worldwide,  most  adults  acquire  at  least  one  sexually  transmitted  infection  (STI),  and  many  remain  at  risk  for  complications.  Each  day,  for  example,  more  than  1  million  STIs  are  acquired  worldwide,  placing  many  affected  persons  at  risk  for  adverse  reproductive  health  outcomes  and  neoplasia.  Certain  STIs,  such  as  syphilis,  gonorrhea,  HIV  infection,  hepatitis  B,  and  chancroid,  often  occur  in  highly  interconnected  sexual  networks  characterized  by  high  rates  of  partner  change  or  multiple  concurrent  partners.  Such  networks,  for  example,  often  include  persons  who  engage  in  transactional  sex,  men  who  have  sex  with  men  (MSM),  and  persons  involved  in  the  use  of  illicit  drugs,  particularly  methamphetamine.  Other  STIs  are  distributed  more  evenly  throughout  populations.  For  example,  chlamydial  infections,  genital  human  papillomavirus  (HPV)  infections,  and  genital  herpes  can  spread  efficiently  even  in  relatively  low-risk  populations.  Finally,  modern  technologies  based  on  detection  of  nucleic  acid  have  accelerated  elucidation  of  the  role  of  sexual  transmission  in  the  spread  of  some  viruses,  including  Ebola  virus  and  Zika  virus,  and  have  provided  new  evidence  of  apparent  sexual  transmission  of  several  bacteria,  including  group  C  Neisseria  meningitidis  and  anaerobes  associated  with  bacterial  vaginosis  (BV).