RT Book, Section A1 Khattar, Ramni A1 Vlahovich, Kevin A1 Sood, Akshay A2 Boulton, Matthew L. A2 Wallace, Robert B. SR Print(0) ID 1188599337 T1 Pneumoconiosis T2 Maxcy-Rosenau-Last Public Health & Preventive Medicine, 16e YR 2022 FD 2022 PB McGraw Hill PP New York, NY SN 9781259644511 LK accessmedicine.mhmedical.com/content.aspx?aid=1188599337 RD 2024/03/29 AB Pneumoconiosis is a general term for a collection of lung diseases caused by the inhalation and accumulation of usually inorganic dust particulates, generally from the workplace, and eliciting an injurious reaction of the lung tissue. Inhalational dust exposure can lead to benign and malignant diseases of the lung parenchyma, airway, and pleura. In this chapter, we outline the nonmalignant respiratory effects related to inhalational exposure to coal mine dust, asbestos, and silica; metals such as uranium and cobalt; as well as man-made vitreous fibers. As shown in Fig. E1-1, parenchymal pneumoconiosis may be classified as nodular lung diseases (including progressive massive fibrosis or PMF), dust-related diffuse pulmonary fibrosis (or secondary usual interstitial pneumonitis or UIP), other interstitial pneumonitis (including hypersensitivity pneumonitis from organic components of the dust), and alveolar proteinosis. Airway-dominant pneumoconiosis may be classified as the chronic bronchitis and/or emphysema phenotypes of chronic obstructive pulmonary disease (COPD), work-related asthma, and small airways diseases. Pleural changes of pneumoconiosis include pleural effusions, rounded atelectasis, circumscribed pleural thickening/pleural plaques, and diffuse pleural thickening. This chapter not only focuses on the nodular and fibrotic parenchymal lung diseases, but also considers the other protean manifestations of pneumoconiosis.