RT Book, Section
A1 Stringer, Janet L.
SR Print(0)
ID 1187633957
T1 Narcotics (Opiates)
T2 Basic Concepts in Pharmacology: What You Need to Know for Each Drug Class, 6e
YR 2022
FD 2022
PB McGraw-Hill Education
PP New York, NY
SN 9781264264841
LK accessmedicine.mhmedical.com/content.aspx?aid=1187633957
RD 2024/04/20
AB The  word  narcotics  (or  opiates)  refers  to  drugs  that  act  on  specific  receptors  in  the  central  nervous  system  (CNS)  to  reduce  perception  of  pain.  In  general,  they  do  not  eliminate  pain,  but  the  patient  is  not  as  bothered  by  the  pain.  They  act  on  three  major  classes  of  receptors  in  the  CNS,  called  opioid  receptors  and  designated  mu  (μ),  kappa  (κ),  and  delta  (δ).  Most  of  the  actions  of  the  narcotic  analgesics  are  mediated  by  the  μ  receptor.  Some  actions  are  mediated  through  the  κ  and  δ  receptors.